Pursue: Undergraduate Research Journal

Aim and Scope

Pursue Undergraduate Research Journal

The scholarly journal, "PURSUE", provides undergraduates an avenue to publish their original research articles in the following areas: (but not limited to) psychology, sociology, biology, chemistry, physics, engineering, computer science, mathematics, humanities, agriculture, architecture, business, and education.

The original research articles included in this journal are peer-reviewed and selected by the journal's Editorial Board. The review process allows undergraduate researchers to receive feedback from notable scientists in their field of study and teach them about the publication process. Publishing their work will not only inform the scientific community but also impact the greater society.

The journal is housed at Prairie View A&M University, a Historically Black University, and is available to all young scientists conducting research. This journal also serves as a means for faculty to extend knowledge beyond the classroom and encourage other students to conduct quality research. All undergraduate research is produced in conjunction with a faculty mentor and is peer reviewed. The journal is open to undergraduates from all Colleges and Universities.

Executive Editor

Dr. Felecia M. Nave
Professor, Chemical Engineering
Provost & Senior VP, Academic Affairs
Prairie View A & M University

Managing Editors & Co-Founders

Dr. Audie K. Thompson
Research Assistant Professor
Chemical Engineering
Prairie View A & M University

Dr. Yolander R. Youngblood
Assistant Professor
Biology
Prairie View A & M University

For more information, please contact us at pursue@pvamu.edu.

Volume 1, Issue 1, 2017

Contents

Square or not Square -- That's the Question!

Alexandra Cromer, Falonne Moumbogno T. Colbie,
Nia Parker, Steven Wang, Hao Wu, Hua-Jun Fan, Ph.D.

Most heavy metals from industrial catalysts are harmful to human body; however, to function normally, the human body does need traces of essential metal cofactors. The data confirms that complexes between cobalt ions and deprotonated histidine will only settle into a square planar geometry, regardless of the initial geometry. However, with neutral histidine, the complex is not in square planar formation at all. Instead, the five-member ring formed among cobalt and histidine's N- and C-terminus forms an angle, where N-Co-N is almost linear (167.5°). Different reaction conditions will yield either tetrahedral and square planar geometry at the metal center, which will influence the band gap. Such influence can then be used to create a tunable and broad spectrum solar panel materials.

Assessment of Keratitis Damage in an Age Dependent
Mouse Model Using Analytical Software

Emmanuel B. Olorunyomi, Miles E. DuBose,
Quincy C. Moore III, Ph.D., and Cleveland O. Lane Jr., Ph.D.

This study analyzed images of the established Keratitis pneumococcal mouse model. The eye images of mice 7-8-week-old and 9-month-old were collected. Additional images were taken on post-infection days one, three, five, and nine, revealing the progression of the infection. Results: The ImageJ Application provided more in depth review to determine the detrimental effects of S. pneumoniae. Through the software, a "Color Threshold" was created on every image to emphasize the area of damage caused by the bacteria. ImageJ has proven to be a useful tool to analyze the impact of disease on the murine model. Results from this study also provide evidence of the importance of early intervention in ocular disease.

Proposing Drug Target(s) to Combat
Trypanosoma brucei Infection

Taylor McGowen and Max W. Fontus, Ph.D.

Sub-Saharan African countries are plagued by an adaptable parasite, Trypanosoma brucei, T.b., with a very high iron dependency. This protozoan parasite is the causative agent for Human African Trypanosomiasis (HAT), otherwise known as sleeping sickness. Any process, which contributes to further decreasing DHAP concentration, is likely to be detrimental to the T. brucei. Other processes, such as superoxide radical degradation, will be considered in concert to the ones assessed in this study to develop suitable drug targets.

Agricultural Vinegar as a growth control agent for both
Glyphosate susceptible (GS) Amaranthus palmeri and
Glyphosate resistant (GR) Amaranthus palmeri

Frank Garcia and Yolander R. Youngblood, Ph.D.

Annually farmers in the United States suffer crop losses due to the invasive weed, Amaranthus palmeri. Agricultural Vinegar (vinegar with 20% acetic acid) is an effective, non-selective organic herbicide. Overall, the experiments show that if caught early enough, with in the first 30 days, the young A. palmeri may be treated with applications of 10% acetic acid or 20% acetic acid regardless of its glyphosate resistance. This is beneficial for the environment because it will decrease the buildup of acetic acid in the soil. This minimizes the chance for making the soil and surrounding environment more acidic. It also brings down the price per acre of producing produce. This in turn brings down the price at the supermarket. Future work can refine what concentration between 10 and 20% remains effective, and further analysis of how the herbicide affects the soil could also lead to more discovery, optimization and further savings.

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